Have you been diagnosed with Chronic Lymphocytic Leukemia (CLL) that has transformed to aggressive lymphoma called Richter's Transformation (RT)? Then you may be able to participate in this study whose purpose is to evaluate the efficacy and safety of glofitamab as monotherapy and in combination with polatuzumab vedotin or atezolizumab for participants with Richter's Transformation (RT) that has transformed from chronic lymphocytic leukemia (CLL). These are targeted immune-based therapies standardly used to treat lymphoma and/or other cancers that may also work well for RT

In this study, we want to learn more about the impacts of displacement due to a natural disaster in the United States. We are looking for professionals with experience in climate change and disaster mitigation and for those displaced due to a natural disaster. Findings from this study may help us understand how state infrastructure may impact climate change resiliency.

Have you been diagnosed with breast cancer and completed your surgery? Has your doctor recommended hormonal therapy to help prevent your cancer from returning? You may be able to participate in a research study of a new drug called Camizestrant. Please reach out to the research team if you are interested and we will provide information regarding the next steps.

In this study, we want to improve virtual healthcare by seeking feedback from those who have used virtual care (ex. telehealth, or e-visits). We are looking for patients, administrators, providers or policymakers to provide feedback through individual, private interviews. Your perspective will help us to foster equitable and sustainable virtual care solutions.

Are you experiencing symptoms of depression that have not been relieved by prescribed anti-depressant medication? If you have taken one or more prescribed anti-depressants and are still feeling symptoms of low mood, anxiety, sleep disruption, or appetite changes, you may be able to take part in a new medication trial for people who have not found other anti-depressants to help them. Compensation will be provided.

Do you have ovarian, peritoneal, or fallopian tube cancer that came back after receiving standard therapy? If so, you might be able to take part in a study that looks at a new treatment, iC9.CAR.B7-H3 cells, to test the safety of these cells and observe any side effects.

We want to improve emergency stroke care across the state of North Carolina. We are doing this by gathering information from individuals like you about emergency stroke services. Your perspective as a stroke patient or caregiver to a stroke patient in North Carolina will help us identify challenges in stroke care and develop effective solutions for those challenges.

In this study, we want to learn how people find and understand information. We want to see how this information affects their lives and their thoughts on money.

Do you want to share your journey of overcoming addiction and nurturing a positive environment for your child? We are listening. If you or your partner are a parent in recovery with a child aged 6-12, you may be able to participate in a study that helps families facing similar challenges. Compensation and childcare will be provided.

Are you living with HIV? Do seek your care at the UNC Infectious Diseases Clinic? If so, you are eligible to participate in Database study! Participating is at no expense to you, and there are no study visits. You would be contributing to increasing knowledge about HIV and furthering the HIV research field.