We are interested in talking to people with chronic pain about their experiences of receiving treatment in the UNC Health System, especially times that they felt particularly empowered or disempowered. Participation includes one focus group lasting 60 to 90 minutes.

Testing Radiation Therapy with or without Cisplatin for Head and Neck Cancer

This project aims to test the cognitive mechanisms involved in language production by healthy adults.

Are you living with obesity? Will you be willing to lose 25% of your body weight? You may be able to participate in a study to see if an investigational medication works better than placebo for weight loss. Eligible participants may also be able to enroll in an extension phase after the main study is done, where they will be guaranteed to receive the investigational medication.

Are you a young adult who drinks and uses social media? We are holding in-person workshops in downtown Chapel Hill to gather feedback from young adults who drink and use social media. Compensation provided.

Do you have plaque type psoriasis? You may be able to participate in a research study to find out if an investigational medication (zasocitinib) works better than an already FDA approved medication for psoriasis (deucravacitinib).

This research study seeks to improve the treatment of early-stage breast cancer by examining circulating tumor DNA (ctDNA). CtDNA, a biomarker found in the blood, may indicate the presence of residual disease after initial treatment. The study aims to determine if ctDNA analysis can help doctors personalize adjuvant therapies, such as radiation and systemic therapy, leading to more effective treatment plans. A significant focus is placed on including African American/Black patients, a population often underrepresented in genomic research. By analyzing ctDNA in this group, researchers hope to gain valuable insights into the disease's characteristics and improve treatment outcomes, ultimately reducing disparities in breast cancer care. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.

Are you currently using insulin to treat type 2 diabetes? Are your blood sugar values still not where your provider wants them to be? If you are willing to use an automated insulin delivery system, involving an insulin pump and a continuous glucose monitor, you may be eligible to participate in a research study to find out if the twiist system can improve glycemic control.

In this study, we want to see if a new drug called LBS-007 can help treat or cure leukemia. We want to find out if it is safe and if it works well for people with this disease.

Big Discoveries Start Small! Looking for Young Explorers to Join Our Screen Time Study Have a child ages 3-8? Spectra Discovery is a one-week research study exploring how wearable devices might track screen time in young children. Your child will wear fake glasses, a shirt clip, and a belt activity counter while using a study-provided tablet. Parents will complete brief daily surveys and device logs. Orientation can happen at home or at our Chapel Hill office. Parents are compensated, and kids receive a special thank-you gift! Help us better understand screen use in children-click to learn more.