This study is being conducted to see how well a study drug called ponsegromab works and if it might improve health and quality of life compared to a placebo in adults who have cachexia (a condition causing significant unintentional weight loss and muscle wasting) and metastatic pancreatic cancer, for which they receive initial chemotherapy.

Are you a Korean speaker living in the U.S. who has used a medical interpreter in a hospital? We are conducting a study to learn about your communication experiences with interpreters and healthcare providers. You can choose to complete a short online survey or participate in a one-on-one interview in Korean. You may enter a drawing based on chance in which each participant has equal odds of receiving the incentive for the survey and receive a gift card for participating in the interview. The study has been modified to broaden the survey participant criteria to include individuals who have not used medical interpreter services, in addition to those who have.

We're doing this study to understand how a type of genetic material called DNA in the blood changes in people with a specific type of cancer that has spread to only a few places in the body. By looking at how this DNA behaves before and after cancer treatment, including radiation, we aim to learn more about how the cancer responds. To do this, we'll collect blood and tumor samples from you to analyze what's happening. This could help in better understanding and improving cancer treatments for others in the future.

Do you have IgE mediated food allergies? Are you interested in the benefits of anti-IgE medications but are hoping to receive fewer injections? RPT904 is expected to work by blocking IgE antibodies, similar to a United States Food and Drug Administration (FDA) approved drug called omalizumab (available as Xolair® or generic omalizumab). However, RPT904 is designed to stay in the body longer than omalizumab and therefore require fewer injections.

Are you feeling a lack of interest in your hobbies, overwhelmed, or disconnected? If you are EITHER experiencing regular menstrual cycles OR more than a year from your last menstrual period, you may be able to participate in a research study to better understand the brain across the menopause transition. Compensation provided.

What if midlife women, who are inherently at an increased risk for future cardiometabolic disease due to transitioning into menopause, had access to a suite of evidence-based health interventions? Could these interventions reduce menopause-related inflammation, restore a healthier cardiometabolic profile, reverse epigenetic aging, and reduce bothersome menopausal symptoms? The ultimate goal of this work is to attenuate future disease and enhance women's quality of life, extend healthspan and increase productivity.

Are you living with primary biliary cholangitis (PBC) and are taking or plan to take elafibranor for your condition? Consider joining our registry study to help advance treatment options and patient quality of life with this condition. We invite you to participate to discuss your experience and the impact on your condition seen with elafibranor. By joining, you'll contribute to understanding the effectiveness and safety of elafibranor in treating PBC. The study aims to evaluate its impact on itching, fatigue, sleep, and overall quality of life. Your participation is voluntary, and you can withdraw at any time without losing medical benefits. With approximately 424 participants globally, you'll continue to receive treatment as usual during the 5-year study period. Plus, you'll have opportunities to discuss your experience with our team and have your voice heard regarding your experience with elafibranor and it's effect on your quality of life with PBC.

Do you have epilepsy and wish that exercise programs actually fit your needs? If you are diagnosed with epilepsy, are 18 years or older, and live in the United States, you may be able to participate in a research study by completing a brief, anonymous online survey about your exercise preferences and what helps or makes it harder to stay active as a person with epilepsy. You could also enter a drawing to win one of five, $50 Amazon gift cards with an equal probability of winning.

Are you due for a colonoscopy in the next 3 years? Has your doctor suggested a blood test called Shield to check for colon cancer? If you answered yes, you might be able to join a study to see how well the Shield test works compared to a colonoscopy.

Are you tired of answering the usual questions about things like gender, race, and income on surveys? We need your help! We want to make these questions better to understand everyone's health needs in the U.S. Participating is easy and helps improve the way we ask these important questions. Interested? Join us today!