Do you have high blood pressure and at least once a day? If so, you may be able to participate in a research study that uses a survey to understand the eating habits and nutrition needs of men living with hypertension. Compensation provided.
The purpose of this study is to compare the effectiveness of 6 months of HER2-targeted medications (trastuzumab with or without pertuzumab) versus 12 months of HER2-targeted medications at reducing the risk of breast cancer coming back or death in patients with early-stage HER2+ breast cancer who had a pCR after preoperative chemotherapy combined with trastuzumab. This study will help the study doctors find out if this different approach is better, the same, or worse than the usual approach. To decide if it is better, the study doctors will be looking to see if the study approach prevents your cancer from coming back compared to the usual approach. Post-surgery trastuzumab with or without pertuzumab is already approved by the FDA for use in early-stage HER2+ breast cancer. There will be about 1524 people taking part in this study.
We are doing this study to test a behavioral weight loss program designed specifically for adolescent and young adult cancer survivors. Study participants will use technology, including a digital smart scale, Fitbit activity tracker, and study web app to help them lose weight.
Have you had trouble getting your child's asthma medication filled at the pharmacy? Have you been inconvenienced because of problems with the prescription, lack of insurance coverage for the drug, or need for a prior authorization? We want to hear from you about the problems you've faced and how we can make getting your child's asthma medication easier and more convenient. We are conducting a research study of caregivers that involves one virtual discussion session with a researcher and other caregivers of children with asthma. You will be compensated for your time.
To determine if neoadjuvant immunotherapy combined with response-adapted oncologic surgery improves site-reported event-free survival (EFS) compared to standard-of-care surgery in resectable stage III/IV cutaneous squamous cell carcinoma (CSCC)
Are you between the ages of 18 and 35 or 65 and 85? Are you interested in contributing to research that wants to understand how human memory works? If so, you may be able to take part in a study on how younger and older adults learn and remember words. You can help us learn more about how memory works in adults! Compensation provided.
Do you feel like your mood is affected by your menstrual cycle? Do you feel like your social media use changes depending on your mood? If you experience a regular menstrual cycle, you may be eligible to participate in a research study to better understand the factors that influence mood and social media use across the menstrual cycle. Compensation provided.
We're trying to find out if a special gel is safe and easy for people with cervical cancer to use. This is for those who are also getting chemotherapy and radiation. We want to see if the gel does its job well, is quick to use, and helps keep healthy tissues safe.
Radiation treatment for head and neck cancer can often cause a very dry mouth. This dryness can last for a long time, even after the treatment ends. In our study, we want to see if changing where the radiation is aimed can help with this dryness. If you join, you'll fill out some simple questionnaires and give saliva samples. We'll also check in with you for about a year after your treatment to see how you're doing.
You are being asked to take part in this study because you have triple negative (TN) breast cancer that has spread to your lymph nodes. You are also planning to get chemo-immunotherapy treatment before surgery. Radiation therapy (RT) has been shown to improve the body's immune response against tumors when it is given with a drug called pembrolizumab. The purpose of this study is to find the best and safest dose of radiation (low or high) when given with pembrolizumab. Radiation is measured in Gy (pronounced "gray"). You will be randomly assigned (like flipping a coin) to receive either a low dose RT boost (9 Gy) or a high dose RT boost (24 Gy). The RT will be given with one dose of pembrolizumab. This is a hybrid decentralized study where some if not all assessments may be performed close to your home.