Exercise has been shown to be beneficial for the management of common adverse effects of cancer and its treatment such as fatigue, anxiety, depression, changes in strength and physical function, and sleep disruption. Get Real and Heel provides participants with the opportunity to obtain these benefits, regardless of cancer type and disease stage, and without cost.

Do your emotions and moods change quickly? Are you shy? If you answered "yes" to any one of those questions, you may be eligible to participate in a paid study on decision-making and brain development.

Have you recently had an anterior cruciate ligament injury and will be undergoing anterior cruciate ligament reconstruction surgery? If so, you may be able to participate in a study comparing the effects on pain relief and arthritis prevention of metformin or placebo. Compensation provided.

Do you have Stage II or III Breast cancer? If you have enough tissue from your breast cancer diagnosis to send for Mammaprint genomic testing, you may be able to take part in this research study. In this study, we want to learn more about adding an immunotherapy drug, durvalumab, to your chemotherapy treatment. The Mammaprint testing is conducted at no cost to you and the cost of durvalumab is covered.

To find out if the study drug AZD9829 is safe and tolerable and effective in treating blood cancer.

This study is being done to answer the following question: Can we extend your life after the diagnosis of your cancer in the stomach, esophagus, or gastroesophageal junction by adding a third chemotherapy drug to the usual combination of two chemotherapy drugs? We are doing this study because we want to find out if this approach is better or worse than the usual approach for treatment of your cancer in the stomach, esophagus, or gastroesophageal junction. The usual approach is defined as care most people get for cancer in the stomach, esophagus, or gastroesophageal junction.

Are you a young adult cancer survivor who would like to lose weight? Interested in using technology to support a healthy diet, get more physically active, and improve your mental health? Researchers at the University of North Carolina at Chapel Hill are looking for volunteers to sign up for a 6-month research program that will involve using a Fitbit activity tracker, digital smart scale, and mobile app. For more information and to see if you qualify, visit our study website at www.uncweightresearch.org

The iTREAT study will compare different ways of treating asthma: a pill or adding a second inhaler to see if they reduce the need for emergency care or going to the hospital.

Do you have a child ages 9-12? Do you live in rural North Carolina? You may be able to participate in a research study that is exploring how parents, particularly in rural areas, want to have conversations about HPV vaccination with their children's' doctors and nurses. Compensation provided.

This is a study to test the dosing and safety of the drug AB248 for people who have an advanced melanoma tumors and who have previously received systemic therapy.